For those geneticists out there, some of the “problems” include coding for the transformation of growth factor β pathway and appear to be localized to a group of genes on the 7q22 chromosome. I am not a genetics expert, so I won’t pretend to explain all the details of these heritable contributors to arthritis; but I have seen and talked to enough patients and I have read enough research to know that the link is very real.

G-RMSEMF1342